Advances in CKD biomarkers

September 21, 2024
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Advances in CKD biomarkers

Advances in chronic kidney disease (CKD) biomarkers have focused on early detection, disease progression, and treatment response. Some of the key developments include:

  1. Kidney Injury Molecule-1 (KIM-1): A promising biomarker for early tubular injury, KIM-1 can detect CKD progression before clinical symptoms appear.
  2. Neutrophil Gelatinase-Associated Lipocalin (NGAL): Widely studied for acute kidney injury (AKI), NGAL is now recognized as an indicator of early CKD and progression risk.
  3. Cystatin C: An alternative to creatinine for estimating glomerular filtration rate (GFR), Cystatin C is more sensitive to mild kidney impairment and cardiovascular risk in CKD patients.
  4. Fibroblast Growth Factor 23 (FGF-23): A marker of mineral metabolism, FGF-23 levels rise early in CKD, predicting cardiovascular events and mortality risk.
  5. Urinary albumin-to-creatinine ratio (UACR): This classic marker for kidney damage is being refined with improved detection methods for microalbuminuria.
  6. Genetic and proteomic biomarkers: Emerging genomic and proteomic analyses are identifying new molecular signatures for individualized CKD prognosis and therapeutic targets.

These advances aim to improve CKD diagnosis, monitor disease progression more effectively, and personalize treatment approaches.

The Migraine And Headache Program™ By Christian Goodman This program has been designed to relieve the pain in your head due to any reason including migraines efficiently and effectively. The problem of migraine and headaches is really horrible as it compels you to sit in a quiet and dark room to get quick relief. In this program more options to relieve this pain have been discussed to help people like you.